Microscopic Polyangiitis (MPA) is inflammation of the small and sometimes medium sized blood vessels. In the past MPA was thought to be a type of PAN and patients would have been told they had PAN. It is now recognised that they are separate diseases.
In microscopic polyangiitis it is common for the smallest blood vessels (capillaries) of the lungs and kidneys to be damaged leading to reduced kidney function or kidney failure and breathlessness.
The current review is a so called Article 20 non-pharmacovigilance procedure. This type of procedure is used when questions arise about the scientific basis or robustness of the data that supported the original approval of a medicine.
It is not started because of new safety problems or concerns about side effects for patients.
In November, patients, caregivers, clinicians and researchers from more than a dozen European countries met in Prague for the 2025 European Vasculitis Patient Summit.
A landmark review in Nature Reviews Rheumatology calls for a new, integrated approach to ANCA-associated vasculitis.When diagnosis, classification, biomarkers and patient experience come together, care becomes truly personal — and outcomes improve.
